8/23/2023 0 Comments Auditory cortex function![]() Our findings suggest that the residual level of consciousness in pDoC patients can be assessed by measuring brain responses to different stimulations using fNIRS. Additionally, the mean concentrations of HbO/HbR increased as the level of consciousness decreased during passive stimulation. However, the hemodynamic responses of the patients with pDoC were opposite to those of the HC. ![]() The results showed that the mean concentrations of HbO/HbR in the prefrontal cortex of the HC during the passive stimulation were significantly lower than those of the active stimulation, and the fitting slope was high. All participants accepted two types of external stimuli, i.e., active stimulation (motor imagery, MI) and passive stimulation (subject’s own name, SON). In this study, fNIRS was used to evaluate the brain function in 18 patients with pDoC, including 14 vegetative states (VS) and 4 minimally conscious states (MCS), and 15 healthy controls (HC). However, the number of fNIRS studies assessing residual awareness in patients with pDoC is still limited. Functional near-infrared spectroscopy (fNIRS) can be used to detect brain activity through changes of oxygenated hemoglobin/deoxygenated hemoglobin (HbO/HbR) concentrations changes and has recently gained increasing attention for its potential applications in assessing residual consciousness. Thus, accurate assessment of residual consciousness in patients with pDoC is important for the management and recovery of patients. Treating prolonged disorders of consciousness (pDoC) is challenging.
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